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Klippel , A. Muslin, W. Fantl, L. Williams, Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Dudek, S. Datta, T. Franke, M. Birnbaum, R. Yao, G. Cooper, Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science, , — Brunet, A.
Bonni, M. Zigmond, M. Lin, P. Juo, L. Hu, Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell, 96 , — Bonni , A. West , S. Datta, M. Takasu, M. Greenberg, Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and independent mechanisms. Maggirwar, P. Sarmiere, S. Dewhurst, R. Freeman, Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons. J Neurosci, 18 , — Datta, H. Dudek, X Tao, S. Masters, H. Fu, Y. Gotoh, Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery.
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Stennicke, G. Salvesen, T. Franke, E. Stanbridge, Regulation of cell death protease caspase-9 by phosphorylation. Gaudet Suzanne, Janes A. Kevin, Albeck G. John, Pace A. Emily, Lauffenburger A. Douglas, and Peter K. Sorger A compendium of signals and responses trigerred by prodeath and prosurvival cytokines, Manuscript MMCP, July 18, Van der Kaay, I.
Batty, D. Cross, P. Watt, and C. Downes, A novel, rapid, and highly sensitive mass assay for phosphatidylinositol 3,4,5-trisphosphate PtdIns 3,4,5 P3 and its application to measure insulin-stimulated PtdIns 3,4,5 P3 production in rat skeletal muscle in vivo J. Hemmings, Akt signaling: linking membrane events to life and death decisions Science, , — Schmoll, K. Walker, D.
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Alessi, R. Grempler, A. Burchell , S. Guo, R. Walther, T. Unterman Regulation of glucosephosphatase gene expression by protein kinase B alpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent effects of insulin on promotor activity.
Chem, , Simulations indicate that the device is suitable to operate at much higher bit rate and also for different logical entities. Many lower-speed data streams can be multiplexed into one high-speed stream by means of Optical time division multiplexing OTDM , such that each input channel transmits its data in an assigned time slot.
The assignment is performed by a fast multiplexer switch mux. The routing of different data streams at the end of the TDM link is performed by a demultiplexer switch demux and this demultiplexer is employed using MZI switch as it consists a semiconductor optical amplifier SOA and a optical coupler.
Uchiyama, H. Takara, K. Mori, T. Shake, H. Takara, I. Ogawa, T.
Kitoh, M. Okamoto, K. Magari, T. Ohara, S. Le-Minh, Z. Ghassemlooy, W. Heid, S. Spalter, G.